After the first few missions have told the story of the movie, gamers play as three of their favorite characters in a quest to save their woodland home from being over-run by a housing development project. Players are challenged with 20 unique, heist-oriented missions in some of the most visually exciting 3D platforming gameplay ever seen on the NDS. The game is shown on both screens and players can use the NDS microphone to distract and surprise enemies. Gamers can play with a friend in the wireless mini-game with a single Over the Hedge NDS cartridge.